Aside

Download in PDF

Contact

Programming Skills

R
Bash
Python
Web Development
SQL

Other Skills

Highly experienced in:

Motivated and collaborative, recently involved in NGS data analysis and genomics prediction

More info

See full CV at ruizsergio.com/cv for a complete list of positions, publications and more

Disclaimer

photo

Source code available in github

Last updated on Jun 23, 2021

Main

Sergio Ruiz-Carmona

I am currently a Research Officer and Bioinformatician at the Baker Institute, under the supervision of professor Mike Inouye. My research interests are broad and involve mainly the relationship between genetic variants and their effect on protein structures.

I carried out my MSc and PhD in Barcelona in the Barril Lab, where I worked with different structure-based drug design methods with the aim to improve drug design for non-standard targets.

Selected Education

PhD in Biomedicine

Universitat de Barcelona

Barcelona, ES

2017 - 2012

  • Virtual Screening for novel MoA: Apps. and method developments
  • Development and application of structure-based drug discovery methods
  • Awards: Extraordinary prize for PhD Thesis and Ramon Margalef award for best publication

Selected Positions

Research Officer and Bioinformatician

Inouye Lab
Cambridge Baker Systems Genomics Initiative
Baker Heart and Diabetes Institute

Melbourne, AU

Today - 2019

  • As part of the Baker Bioinformatics facility, I give bioinformatics, statistical and data analysis support to the whole Institute, mainly in projects related with cardiovascular diseases and diabetes

Associate Professor

Faculty of Pharmacy, Universitat de Barcelona

Barcelona, ES

2019 - 2015

EMBO Short-Term Fellow

Andreas Bender Lab, Unversity of Cambridge

Cambridge, GB

2017

  • I spent 2 months in one of the main Pharmacogenomics groups in the world, where I used gene-expression profiles of different biological systems to study BRD4 and drug selectivity

Main Scientific Output

Oxygen Pathway Limitations in Patients with Chronic Thromboembolic Pulmonary Hypertension

Circulation

N/A

2021

  • Erin J Howden *, Sergio Ruiz-Carmona *, […] Andre La Gerche, Marion Delcroix and Guido Claessen
  • Result of a Bioinformatics Core collaboration. Shiny app developed

Loss of the long non-coding RNA OIP5-AS1 exacerbates heart failure in a sex-specific manner

iScience

N/A

2021

  • Aowen Zhuang, A Calkin, […] Sergio Ruiz-Carmona, […] and Brian G Drew
  • Result of a Bioinformatics Core collaboration

Dynamic undocking and the quasi-bound state as tools for drug discovery

Nature Chemistry

N/A

2017

  • Sergio Ruiz-Carmona, P Schmidtke, […] Rod Hubbard and Xavier Barril
  • Highlighted in its issue cover

rDock: a fast, versatile and open source program for docking ligands to proteins and nucleic acids

PLoS Computational Biology

N/A

2014

  • Sergio Ruiz-Carmona, Daniel Alvarez-Garcia, […] Xavier Barril, Rod Hubbard and S David Morley