Main
Sergio Ruiz-Carmona
I am currently a Research Officer and Bioinformatician at the Baker Institute, under the supervision of professor Mike Inouye. My research interests are broad and involve mainly the relationship between genetic variants and their effect on protein structures.
I carried out my MSc and PhD in Barcelona in the Barril Lab, where I worked with different structure-based drug design methods with the aim to improve drug design for non-standard targets.
Selected Education
PhD in Biomedicine
Universitat de Barcelona
Barcelona, ES
2017 - 2012
- Virtual Screening for novel MoA: Apps. and method developments
- Development and application of structure-based drug discovery methods
- Awards: Extraordinary prize for PhD Thesis and Ramon Margalef award for best publication
Selected Positions
Research Officer and Bioinformatician
Inouye Lab
Cambridge Baker Systems Genomics Initiative
Baker Heart and Diabetes Institute
Melbourne, AU
Today - 2019
- As part of the Baker Bioinformatics facility, I give bioinformatics, statistical and data analysis support to the whole Institute, mainly in projects related with cardiovascular diseases and diabetes
Associate Professor
Faculty of Pharmacy, Universitat de Barcelona
Barcelona, ES
2019 - 2015
EMBO Short-Term Fellow
Andreas Bender Lab, Unversity of Cambridge
Cambridge, GB
2017
- I spent 2 months in one of the main Pharmacogenomics groups in the world, where I used gene-expression profiles of different biological systems to study BRD4 and drug selectivity
Main Scientific Output
Oxygen Pathway Limitations in Patients with Chronic Thromboembolic Pulmonary Hypertension
N/A
2021
- Erin J Howden *, Sergio Ruiz-Carmona *, […] Andre La Gerche, Marion Delcroix and Guido Claessen
- Result of a Bioinformatics Core collaboration. Shiny app developed
Loss of the long non-coding RNA OIP5-AS1 exacerbates heart failure in a sex-specific manner
N/A
2021
- Aowen Zhuang, A Calkin, […] Sergio Ruiz-Carmona, […] and Brian G Drew
- Result of a Bioinformatics Core collaboration
Dynamic undocking and the quasi-bound state as tools for drug discovery
N/A
2017
- Sergio Ruiz-Carmona, P Schmidtke, […] Rod Hubbard and Xavier Barril
- Highlighted in its issue cover
rDock: a fast, versatile and open source program for docking ligands to proteins and nucleic acids
N/A
2014
- Sergio Ruiz-Carmona, Daniel Alvarez-Garcia, […] Xavier Barril, Rod Hubbard and S David Morley